infinium genotyping data (INFINIUM Inc)
90
Structured Review
INFINIUM Inc
infinium genotyping data
Infinium Genotyping Data, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/infinium+genotyping+data/infinium+genotyping+data/pmc10275001-101-0-0
Average 90 stars, based on 1 article reviews
Infinium Genotyping Data, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/infinium+genotyping+data/infinium+genotyping+data/pmc10275001-101-0-0
Average 90 stars, based on 1 article reviews
infinium genotyping data - by Bioz Stars,
2026-10
90/100 stars
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1) Product Images from "Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations"
Article Title: Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations
Journal: medRxiv
doi: 10.1101/2023.05.25.23290535
Figure Legend Snippet: Performance measures from the PRS pipeline validation study at the clinical laboratory. PRS pipeline accuracy is assessed as the Pearson correlation between scores derived from PCR-free 30X WGS and those derived from imputed genotyping data (GDA) in the same 70 specimens. Pearson correlation shown in the mean correlation across all ancestry groups tested. PRS pipeline precision (repeatability) is the measure of concordance in PRS scores calculated from the same 70 specimens, run through the pipeline 10 times over the course of two weeks. PRS pipeline precision (reproducibility) is assessed using three samples, each run 6 times end-to-end and then compared in a pairwise manner. The z-score standard deviation is used as a measure of variability. PRS site missingness is the percentage of genomics sites in the original score that are missing from the final imputed dataset. Odds Ratios for high PRS vs Not high pRS are derived from the condition-specific cohorts and calculated by each condition lead group across the ancestries available. Odds ratio information for Obesity/BMI is in preparation for publication by the GIANT consortium.
Techniques Used: Biomarker Discovery, Derivative Assay, Standard Deviation
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